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br Interstitial lung disease br Histology br Driver mutation
2020-08-18
Interstitial lung disease Histology Driver mutations M factor No. of metastatic organs Metastasis within the chest cavity Bone metastasis Brain metastasis Liver metastasis Adrenal gland metastasis Lymph node metastasis Muscle metastasis Skin metastasis CI: co
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br Results As of June patients were
2020-08-12
Results: As of June 2018, 11 patients were recruited. One was excluded from the analysis for presenting severe toxicity, suggestive of dihydropyrimidine dehydrogenase (DPD) defi-ciency, after the first chemotherapy cycle. All others completed the treatment. Two patients presented toxicity grade 3/
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br Patient summary In this study we examined
2020-08-12
Patient summary: In this study, we examined the effect of androgen deprivation therapy (ADT) for Gleason 8 (Grade Group 4) versus Gleason 9–10 (Grade Group 5) prostate cancer. We found that Gleason 9–10 disease may derive a smaller survival benefit from ADT than Gleason 8 disease. © 2018 Europe
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br Results and discussion br It is
2020-08-07
3. Results and discussion It is well-known that the formation of phthalocyanine H-aggregates results in a blue-shift of the low-energy Q-band, reduces phthalocya-nines' fluorescence quantum yield and diminishes PDT activity [43–47]. Thus, it was important to evaluate aggregation behavior of th
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br Materials and methods br Cell culture and
2020-08-07
2. Materials and methods 2.1. Cell culture and cell proliferation assay All cell lines used in this study were originally obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA). DLD-1, HCT-116 (human colon cancer), MDA-MB-231 (human breast cancer), A375P (human melanoma
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br Keywords br Epithelial ovarian cancer br Human
2020-08-06
Keywords: Epithelial ovarian cancer Human chorionic gonadotrophin Luteinizing hormone Luteinizing hormone (LH)/hCG receptor Overall survival In addition to its critical role during pregnancy, human chorionic gonadotropin (hCG) has been shown to be expressed by various tumor types
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br Fig Kaplan Meier curves for PFS and OS
2020-08-05
Fig. 1. Kaplan-Meier curves for PFS and OS according to antibiotic use in the EIOP. PFS = Progression Free Survival. Atb = Antibiotics. EIOP = Early Immunotherapy Period. OS = Overall Survival. Fig. 2. Kaplan-Meier curves for PFS and OS according to AIER during the WIOP. PFS = Pr
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br Statistical analyses br All the
2020-08-03
2.9. Statistical analyses All the analysis were carried out triplicate and obtained values were expressed as the means ± standard deviation (SD) that was calculated by Microsoft Excel 2016. Statistical analyses were performed using Student’s t-test and ANOVA for two groups and multiples compari
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br Every fraction was weighted and
2020-08-03
Every fraction was weighted and completely dissolved with di-methyl sulfoxide (DMSO; Sigma, St. Louis, MO, USA) at the solubility of 200 mg/mL, and then diluted to the final concentrations of 2, 0.5, and 0.1 μg/mL with adenosine triphosphate tumor chemosensitivity assays (ATP-TCA) kit cell culture
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br Determination of Ab MNP Si binding to CFSC stained
2020-08-02
3.4. Determination of Ab/MNP-Si binding to CFSC-stained Temozolomide and separation from whole blood To evaluate the performance of Ab/MNP-Si in the blood and the ability of the nanoparticle-silane-antibody conjugate to separate cancer cells, after cell staining, different amounts of CFSE-stain
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br LMB Targeting CRC br membrane of ovarian cancer OVCAR
2020-07-30
LMB100 Targeting CRC membrane of ovarian cancer OVCAR-3 cells.4 Since then, MSLN has been studied extensively and found to be highly expressed on many malignancies, including pancreatic adenocarcinoma and mesothelioma.5-8 An RIT targeting MSLN named SS1P was con-structed by fusing the Fv portio
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br In addition to the e ect
2020-07-29
In addition to the effect on endothelial cells, we also examined the effect of ANGPTL6 on tumor cells. Different types of cytokines, che-mokines, and other secretory proteins in the surrounding micro-environment were secreted into the tumor bed, and these proteins not only affect the activity of strom
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br Overexpression of a poorly
2020-07-28
Overexpression of a poorly characterized kinase, MGC42105 (NIM1K), in cluster 5 (highlighted in Figure 4D) modulated the phosphorylation of Ser241 on PDK1, Thr389 on p70S6K, and Ser235/Ser236 on S6, suggesting a role in growth signaling. MGC42105 also induced abundance-dependent activation of stre
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br Mobile phone use was estimated from the national
2020-07-28
Mobile phone use was estimated from the national number of cel-lular mobile phone subscriptions obtained and was obtained from the United Nations specialized agency for information and communication technologies (ITU, 2016). data were obtained after a Data Access Agreement with ONS was put in p
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br Our data suggest that gastric cancer organoids
2020-07-28
Our data suggest that gastric cancer organoids may be used to help predict patient response to targeted therapies such as HER2 inhibition. Expression of HER2 within orga-noid cultures (huTGO1 and huTGO2) that were 2 of the resistant lines to chemotherapy treatment was sensitized to these chemother